What type of confrontation develops the plot of a story?

Many different types of confrontations may develop the plot of the story, however, if you are inexperienced as a writer then you may want to go with protagonist and antagonist, give the main character of your story someone who contradicts him in most if not every way. Try to have their conflict put more meaning and interest into your story. However if you are more experienced you could go with anything else, a protagonist vs. another protagonist, you could switch off to man vs. and go with man vs. nature (The character has a confrontation with nature and has to overcome it) man vs self (The character comes to some sort of self realization or has a revelation of some kind and has to battle it out with himself). Basically i could go on forever with this and I'm just trying to make the point that there are many, many possibilities for a way that you could get a confrontation to develop a story, you just need to find one that suits you.