They are known to be carriers of Mycobacterium Leprae (the bacteria which causes Leprosy). This can transmitted through their claws and on occasion, skin contact. They may also transmit Salmonella in their solid waste. That is not to say that every single armadillo carries these bacteria all the time, however many have been found which were carriers.
Like many wild animals they can also be infected with rabies. If you notice an armadillo acting particularly fearless and aggressive around humans and cats or dogs; and/or if it is particularly active during the day (they are mostly nocturnal creatures); suspect rabies infection.
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