Can you use deionized water for injections?

Water for injection must be either purified by distillation (boiling and removing impurities) or by reverse osmosis (passing water through a semipermeable membrane that filters out most impurities). The water must be pyrogen-free (meaning that it does not contain any materials that can induce a fever). Deionized water is not sufficient for injection. Although some drugs are incompatible with ions (and must be removed), most injections require a saline solution or some other isotonic solution for injection. This is so that the cells do not burst upon injection (which can be very painful).