- In a few marine species, gray cells of the sponges primitive "immune" system and can release toxins that kill all cells in the area as part of the rejection of foreign material.
- They also produce toxins that prevent other sessile organisms such as bryozoans or sea squirts from growing on or near them.
- A few species, such as the Caribbean fire sponge, cause a severe rash in humans who handle them and such toxins may protect against predators.
- The Caribbean chicken-liver sponge secretes toxins that kill coral polyps, allowing the sponges to grow over the coral skeletons.
See: http://en.wikipedia.org/wiki/Sponge
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