When ingested in large quantities, the sugar alternative sorbitol and the fat alternative olestra are known to induce gastrointestinal distress, including diarrhea and abdominal cramping. Sorbitol can cause osmotic diarrhea due to its inability to be fully absorbed in the intestines, while olestra can lead to loose stools and other digestive issues by interfering with the absorption of fats and certain vitamins.
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