Can you be on methadone one day and be on suboxone the next day?

wait at least 48 hours, what ever you do , do not take any suboxone before this or you risk getting VERY VERY sick. The half life of methadone is around 60 hours, so if you can stand to wait 3 days (72 hours) than that is better, the longer the better really. You also need to have been gradually coming down off the methadone and need to go down as far as possible. You must be below 40mg but if you can go all the way down to 10 or 15mg than that would make for a smoother transition. You need to be totally honest with your suboxone doctor about when the last time you used was so he can then tell you when to take the suboxone. Trust me you do not want to play around with this. I have seen so many people coming off methadone think " I'll just go ahead and take a suboxone" when it had only been like 24 hours, and the went into severe withdrawals immediately and where in pure HELL for a few hours. No matter how bad you feel just wait wait wait as long as you can. At least 48 hours.