What 2 calamities occurred during the reign of Charles 2?

During the reign of Charles II, two significant calamities were the Great Plague of 1665 and the Great Fire of London in 1666. The Great Plague resulted in the deaths of approximately 100,000 people in London, severely impacting the population and the economy. The following year, the Great Fire devastated a large part of the city, destroying thousands of homes and significant landmarks, leading to widespread homelessness and economic disruption.