What is the name of the first large slave ship to America?

Well, "large" is pretty vague. However, the "20 and odd" Africans that were first brought to the English colonies of America were brought to Jamestown VA in 1607. For some years it was believed they were aboard a Dutch naval vessel, but it now appears it was an English Privateer, the White Lion, that had taken the slaves from a Portugese ship enroute to Mexico.