What is difference between largest and longest gene?

The largest gene refers to the gene with the most base pairs in its DNA sequence, while the longest gene typically describes the gene with the greatest physical length when considering its transcription and processing, including all exons and introns. For example, the dystrophin gene is often cited as the largest gene due to its extensive sequence, whereas other genes might be longer in terms of total transcript length after splicing. Thus, the terms focus on different aspects of gene structure.