What is the best response to the moves 1. e4 e5 2. Nf3 Qf6 in a game of chess?

The best response to the moves 1. e4 e5 2. Nf3 Qf6 in a game of Chess is to continue developing your pieces with 3. Bc4. This move puts pressure on Black's weak f7 square and helps control the center of the board.