What is are 5 differences between NFL football and flag football?

Well in tackle football you have to 4 downs to make it all the way to the endzone. In flag football if the flag on your belt is pulled you have a little more time to make a score.

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90% of rules in Flag versus Tackle are the same. In flag, you cannot make blows to other players including when you block. But the specifics vary from local league to local league. Players must all have two flags on a belt that can be pulled off. When pulled off the play is dead right there. That is the equivalent to a tackle. In flag there are no fumbles. If the ball is dropped it is blown dead because you don't want unprotected players diving on the ground for a loose football. In tackle, you have full gear, including a helmet, pants, and shoulder pads.

There are subtle differences between Pee-wee, Jr Pee-Wee, and grasscutters in tackle. For instance, all kids of a certain weight must have a stripe on their helmet and line up between the offensive tackles.

In Middle School, Freshman, JV and Varsity all the rules are typically same and governed by the NFHS. Your local flag football association has rule books you can get that show the rule exceptions to between their rules and those of the NHFS.