Why s.aures colony yellow on msa?

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1161047

2026-04-13 11:20

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Staphylococcus aureus colonies appear yellow on Mannitol Salt Agar (MSA) because they ferment mannitol, producing acid as a byproduct. The acid lowers the pH of the medium, causing the phenol red indicator in the agar to change from red to yellow. This color change is a key characteristic used to differentiate S. aureus from other staphylococci that do not ferment mannitol, which typically result in red colonies.

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