What is physiologic endometrium?

Physiologic endometrium refers to the normal, functional layer of the endometrium, which is the lining of the uterus that undergoes cyclic changes during the menstrual cycle. This tissue thickens in response to hormonal fluctuations, particularly estrogen and progesterone, preparing for potential implantation of a fertilized egg. If pregnancy does not occur, the endometrium sheds during menstruation. The physiologic endometrium is essential for reproductive health and plays a key role in fertility.