Running out of cards in canasta?

In Canasta, running out of cards occurs when a player has no more cards in their hand to play or draw from the stockpile. This situation typically arises when a player has melded all their cards or has successfully played their last card. Once a player goes out, the round ends, and players calculate their scores based on their melds and any remaining cards in their hands. It's a strategic move, as going out can impact the overall score and the flow of the game.