How long does xifaxan stay in your system?

Xifaxan (rifaximin) has a relatively short half-life of about 5 to 6 hours in healthy adults. It is typically eliminated from the body within 24 hours after the last dose, although some metabolites may linger longer. However, the duration can vary based on individual factors such as metabolism, age, and kidney function. Always consult a healthcare professional for personalized information.