Did colt make a revolver in .25-.20 caliber?

Yes, Colt produced a revolver chambered in .25-20 caliber, specifically the Colt New Police revolver, which was designed to fire the .25-20 WCF (Winchester Center Fire) cartridge. This revolver was part of Colt's efforts to offer a small, pocket-sized firearm suitable for self-defense. The .25-20 caliber was not as common as other calibers, but it was available in some of Colt's models during the early 20th century.