Can you drive with your gun?

It depends on what you mean. If you mean, can you have a gun in your car, the answer is, it depends. Some states, such as Mississippi, allow a person to carry a gun in the car even if the person doesn't have a permit, because the car is considered an extension of your home.

Other states, such as Tennessee, allow car carry only if you have a valid handgun carry permit.

Federal law allows you to transport an unloaded firearm in your car while travelling if the gun is unloaded and not accessible to you, so even if you don't have a permit, you can transport a firearm from one place to another, even if you don't have a permit, as long as you can legally possess the gun.