What were the effects of smallpox on the population of Tenochtitlan?

Smallpox had devastating effects on the population of Tenochtitlan following its introduction by European colonizers in the early 16th century. The disease spread rapidly among the indigenous people, leading to high mortality rates, with estimates suggesting that up to 90% of the population may have died from the epidemic. This dramatic decline in population weakened the social and political structures of the Aztec Empire, making it more vulnerable to Spanish conquest. Additionally, the loss of a significant portion of the population disrupted agriculture and labor, further exacerbating the crisis.