Tommy Byrne Did he ever throw over 300 pitches in a game?

Yes, Tommy Byrne, a former Major League Baseball pitcher, is famously known for throwing over 300 pitches in a single game. This occurred on September 6, 1948, while he was playing for the New York Yankees in a game against the Chicago White Sox. His remarkable endurance and the high pitch count have become a notable part of baseball history, although such practices are considered highly unsafe by modern standards.