Did Manchester united ever lose the first three matches in a season and then go ahead to win the the Barclay's premier league?

Yes, Manchester United lost their first three matches of the 2013-2014 Premier League season. Despite this rocky start, they did not go on to win the league that season; they finished seventh. Historically, it is very rare for teams to recover from such a poor start to claim the title, and Manchester United's situation in that season exemplifies that challenge.