twilight book series-
Unless they are newly changed (Bree) or lived a particularly violent life (Jasper) then yes they can, with one exception to the rule. One of Bella's special abilities is to control her thirst.
real life-
That depends on the person. Self control is the key. A ...friend... of mine is going through the same thing. He has found a way to deal by using his affinity for the moon (he's a cancer) to calm himself during ...bad times... Friends always help- especially those who know and accept the vamp(s). However he does get rather unstable during the full moon... Recently though we have accepted a ...divine... help into our group, and he really seemed to make a difference in the amount of thirst at any given time.
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