Proteins that remain on the side of the lipid bilayer are typically referred to as peripheral or extrinsic proteins. These proteins are not embedded within the lipid bilayer but are loosely attached to the exterior or interior surfaces of the membrane, often through interactions with integral proteins or lipid head groups. They play key roles in signaling, maintaining cell shape, and facilitating communication between the cell and its environment. Examples include spectrin and certain enzymes that are involved in cellular processes.
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