Which planet or planets vary most from the general pattern of spacing?

The planets that vary most from the general pattern of spacing in the solar system are Mercury and Neptune. Mercury, being the closest planet to the Sun, has a significantly smaller orbit compared to the other inner planets, resulting in a tighter spacing. Neptune, on the other hand, is much farther out and has a unique orbital distance that deviates from the more consistent spacing of the outer planets, particularly in comparison to Uranus. These anomalies highlight the diverse gravitational influences and formation histories of the planets.