Atenolol is a cardiOSelective beta-blocker, meaning it primarily affects beta-1 adrenergic receptors in the heart, which reduces the risk of bronchoconstriction in patients with COPD, who have sensitive airways. In contrast, propranolol is non-selective and can block both beta-1 and beta-2 receptors, potentially exacerbating respiratory symptoms in COPD patients. Therefore, atenolol is generally preferred for managing cardiovascular issues in this population while minimizing respiratory complications.
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