Yes, the small intestine does have buffers. The primary buffering agents in the small intestine are bicarbonate ions, which are secreted by the pancreas into the duodenum. This bicarbonate helps neutralize the acidic chyme coming from the stomach, creating a more alkaline environment that is optimal for digestive enzymes to function effectively. Additionally, mucus secreted by intestinal glands also contributes to maintaining the pH balance in the small intestine.
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