How can I efficiently pack clothes in luggage for a weekend getaway?

To efficiently pack clothes in luggage for a weekend getaway, roll your clothes instead of folding them to save space and prevent wrinkles. Use packing cubes or compression bags to organize and maximize space in your luggage. Choose versatile clothing items that can be mixed and matched to create different outfits. Pack only essential items and avoid overpacking to keep your luggage light and easy to carry.