A knot 3 inches below the knee could be caused by various factors, including muscle strain or overuse, which may lead to a muscle knot or trigger point. It could also be due to tendinitis or inflammation of the tendons in that area, such as the patellar tendon. Additionally, it may indicate a cyst or a benign growth, such as a lipoma. If the knot is persistent or accompanied by pain, swelling, or other symptoms, it's advisable to consult a healthcare professional for evaluation.
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