How far is it from Cheyenne Wyoming to Lake Tahoe?

The distance from Cheyenne, Wyoming, to Lake Tahoe, California, is approximately 900 miles (about 1,450 kilometers) by road, depending on the specific route taken. The drive typically takes around 14 to 16 hours, depending on traffic and road conditions. If measured in a straight line (as the crow flies), the distance is around 750 miles (about 1,200 kilometers).