Can you take colchicine with diclofenac?

Yes, you can in the sense that there are no identified adverse interactions between them. If you are taking colchicine to prevent gout attacks along with a uric acid lowering drug and experience an attack, an anti-inflammatory can be added. Diclofenac is a nonsteroidal anti-inflammatory. However, your doctor will most likely recommend naproxen, sulindac, or indomethacin instead given that you do not have ulcers in the stomach or upper part of the intestine.