What natural disaster occurred during Justinians reign?

During Justinian's reign, one of the most significant natural disasters was the devastating earthquake in 526 AD. This earthquake struck the eastern Mediterranean, causing widespread destruction in cities like Antioch and resulting in numerous fatalities. Additionally, the outbreak of the Plague of Justinian in 541 AD, although not a natural disaster in the traditional sense, had catastrophic effects on the population and economy of the Byzantine Empire.