Would a male with Down syndrome and a male without Down syndrome have a child with Down syndrome?

== == * I did some research and learned that men with Down syndrome are usually sterile. Most women can get pregnant and have children. Since there is a high risk of Down syndrome in the baby (35%-50%), many times the pregnancy would end in a miscarriage. But many Down syndrome people have had children.

* Technically yes, but it's unlikely. Fertility is greatly reduced in both males and females with Down syndrome, although there have been a few cases of males fathering children and females bearing them.

* Actually, there has only been 1 case of a male fathering a child. A women with Down syndrome can have children, but there is a 50% chance that the baby will be born with Down syndrome.