Is it safe to make gravy from pan drippings left out overnight?

No, it is not safe to make gravy from pan drippings left out overnight. Bacteria can multiply rapidly at room temperature, leading to foodborne illnesses. It is important to refrigerate perishable foods promptly to prevent bacterial growth and ensure food safety. It is recommended to discard any perishable food items that have been left out at room temperature for more than 2 hours.