Why are people who have poor DNA repair mechanisms at greater risk fo cancer development?

People with poor DNA repair mechanisms are at greater risk for cancer development because their cells are less capable of correcting genetic mutations that arise from environmental factors or normal cellular processes. Accumulation of these mutations can lead to uncontrolled cell growth and tumor formation. Additionally, compromised DNA repair pathways can disrupt regulatory mechanisms, further promoting cancerous changes. As a result, individuals with defective DNA repair are more susceptible to the initiation and progression of various cancers.