What are the key steps involved in conducting a Mosher ester analysis?

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1130865

2026-04-16 23:05

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The key steps involved in conducting a Mosher ester analysis include:

  1. Preparing the sample by synthesizing the Mosher esters from the compound of interest.
  2. Analyzing the sample using NMR spectroscopy to determine the chemical shifts of the protons in the Mosher esters.
  3. Comparing the chemical shifts of the protons in the Mosher esters with a reference database to determine the absolute configuration of the original compound.

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