Five U. S. Vice Presidents held elected office in Indiana; Two were born in Indiana as well.
- Schuyler Colfax (VP under Grant 1869-1873)- born in NYC ; Congressman from Indiana
- Thomas A. Hendricks( VP under Cleveland for 8 months 1885) - born in Ohio- Governor of Indiana
- Charles W. Fairbanks ( VP under Theodore Roosevelt 1905-1909) born in Ohio; US Senator from Indiana
- Thomas R. Marshall( VP under Wilson 1913-1921); born North Manchester, Indiana: governor and Senator from Indiana.
- Dan Quayle (VP under George H. W. Bush 1989-1991) born Indianapolis, Indiana; US Senator from Indiana
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