Has anyone used 9mm in a hi-Point 380?

Don't attempt this. Using ammo other than what the firearm is designed for is extremely dangerous, and may result in injury or even death to the firer. Especially in this case, where you're talking about using an entirely separate class of ammo than what the pistol was designed for. The 9x17/.380 ACP is a lower powered round, designed to be used in an unlocked breech pistol. The 9x19/9mm Luger/9mm Parabellum generates significantly more pressure

• too much to be used in an unlocked breech pistol. Even if you can

get it to chamber, you run a serious risk of catastrophic failure.