What is the second stage of syphilis characterized by?

The second stage of syphilis, known as secondary syphilis, is characterized by the appearance of a widespread rash, often on the trunk and extremities, and mucous membrane lesions called mucous membrane pemphigus. Other symptoms may include flu-like signs such as fever, sore throat, and swollen lymph nodes. This stage typically occurs weeks to months after the primary chancre has healed and indicates that the infection has spread throughout the body. If untreated, secondary syphilis can progress to the latent and tertiary stages.