Urine is generally considered sterile when it is produced by the kidneys and stored in the bladder. However, it can become contaminated with bacteria as it passes through the urethra, particularly during urination. In healthy individuals, urine typically does not contain pathogens, but certain conditions or infections can lead to the presence of bacteria or other microorganisms. Thus, while urine in the bladder is sterile, it may not be so once it exits the body.
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