Why is tuberculosis treated with multiple antibiotics?

Tuberculosis (TB) is treated with multiple antibiotics to prevent the development of drug-resistant strains of the bacteria. Mycobacterium tuberculosis, the causative agent of TB, can mutate and become resistant to single antibiotics, making treatment less effective. Using a combination of antibiotics enhances the likelihood of eradicating the bacteria and reduces the risk of resistance. Additionally, the prolonged treatment course of TB necessitates multiple drugs to ensure complete bacterial elimination and promote successful recovery.