Alzheimer's disease is not specifically linked to either the Y chromosome or the X chromosome; it is primarily influenced by a combination of genetic, environmental, and lifestyle factors. While certain genetic mutations associated with familial Alzheimer's can be found on chromosomes 1, 14, and 21, the majority of Alzheimer's cases are sporadic and do not follow a clear inheritance pattern. Some risk factors, like the APOE ε4 allele, are located on chromosome 19, but this is not sex-linked. Overall, Alzheimer's is a complex disorder with multifactorial causes.
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