Can Lyme disease cause low alkaline phosphatase?

Yes, Lyme disease can potentially lead to low alkaline phosphatase levels, although it is not a common finding. Alkaline phosphatase levels may decrease due to liver dysfunction or other systemic effects associated with the infection. It is important to consider other causes of low alkaline phosphatase as well, and a healthcare professional should evaluate any abnormal lab results in the context of the patient's overall health and symptoms.