When a nerve signal reaches the axon terminal, it triggers the influx of calcium ions (Ca²+) into the terminal through voltage-gated calcium channels. This influx causes synaptic vesicles containing neurotransmitters to fuse with the presynaptic membrane, releasing the neurotransmitters into the synaptic cleft. The neurotransmitters then bind to receptors on the postsynaptic neuron, leading to the initiation of a new nerve signal in that neuron.
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