Hypofunction of the thyroid gland, known as hypothyroidism, results in insufficient production of thyroid hormones, which can lead to a range of symptoms including fatigue, weight gain, cold intolerance, and depression. The condition can also cause slower metabolism and various physiological changes. Common causes include autoimmune disorders like Hashimoto's thyroiditis, certain medications, and iodine deficiency. Treatment typically involves hormone replacement therapy to restore normal hormone levels.
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