Hydromorphone typically has a half-life of about 2 to 4 hours, meaning it takes that long for half of the drug to be eliminated from your system. After taking 5 mg three times a day for three days, it may take approximately 1 to 2 days for the drug to be largely cleared from your system, though traces could be detectable for longer depending on individual factors like metabolism and overall health. Always consult a healthcare professional for personalized information.
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