What is the difference between DNA proofreading and mismatch repair?

DNA proofreading occurs during DNA replication and involves the DNA polymerase enzyme checking for errors in base pairing as it synthesizes a new DNA strand. Mismatch repair occurs after DNA replication and involves specialized enzymes that recognize and remove mismatched base pairs that were not corrected during proofreading. In other Words, proofreading happens during synthesis, while mismatch repair occurs after synthesis is complete.