What is ox-42?

Ox-42 is a monoclonal antibody that specifically binds to the CD11b component of the integrin complex, which is primarily expressed on myeloid cells, including microglia and macrophages. It is often used in neuroscience research to label and study activated microglia in various models of neuroinflammation and neurodegenerative diseases. By binding to these cells, researchers can visualize and analyze their activation states and roles in health and disease.