The duration for tongue swelling to subside after taking an antihistamine can vary depending on the individual and the severity of the reaction. Typically, antihistamines can start to take effect within 30 minutes to 2 hours, and swelling may begin to decrease within that timeframe. However, complete resolution can take several hours to days, depending on the underlying cause of the swelling. If symptoms persist or worsen, it's important to seek medical attention.
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