A standard queen-sized quilt typically measures about 90 inches by 90 inches. If you use 12-inch blocks, you can fit 7 blocks across the width (90 inches / 12 inches) and 7 blocks down the length, resulting in a total of 49 blocks (7 blocks x 7 blocks) for the quilt. However, depending on the exact dimensions of the quilt and any borders or sashing, the number of blocks may vary slightly.
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