To calculate the rate for running 250 cc (mL) of normal saline over 20 minutes, you can use the formula: rate (mL/min) = total volume (mL) / time (min). In this case, it would be 250 mL / 20 min = 12.5 mL/min. Therefore, the infusion rate should be set to 12.5 mL per minute.
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