What is the difference between between baptism and confirmation?

Baptism is usually done when you are a baby. Confirmation is usually done when you are near graduating from high school. The difference is that baptism is usually when the parents say that this is the religion that you are going to be practicing and learning about. Confirmation is when you take it upon yourself to say that you are going to continue to learn and follow the religion.

Catholic AnswerBaptism is the sacrament by which (through water and the Word of God) a person is cleansed of all sin and reborn and sanctified in Christ to everlasting life. It is strictly necessary for salvation.

Confirmation is a different sacrament by which, through the laying on of hands, anointing with Chrism, and prayer, those already baptized are strengthened by the Holy Spirit in order that they may steadfastly profess the faith and faithfully live up to their profession. In the early Church it was given immediately after Baptism, in the Eastern Church it is known as Chrismation, as the Confirmed are anointed with Sacred Chrism. Though not strictly necessary for salvation, unlike baptism, confirmation is eminently important in contributing to Christian perfection and there is a grave obligation to receive it in due time.

In all but the Latin rite, Baptism, Confirmation, and Holy Communion are given together upon one's entry into the Church even if this is within a week of birth. In the Latin rite they are separated, often by many years, for infants, they are still given together for adult converts.